AMA #9: Kratom Risks, Does Infrared Sauna Work & Journaling Benefits
Andrew Huberman
26 min, 32 sec
Dr. Andrew Huberman discusses the effects and risks of kratom, a controversial opioid, in an AMA podcast episode.
Summary
- Kratom is an opioid from the tree Mitragyna speciosa, known for its stimulant effect at low doses and sedative, painkilling effects at high doses.
- Kratom acts on mu-opioid receptors similarly to opioids like morphine and hydrocodone, which makes it both habit-forming and addictive.
- Some individuals use kratom to wean off stronger opioids, but it can become a trap, leading to dependence on kratom itself.
- Kratom is not benign; it carries the risk of addiction, withdrawal symptoms, and in high doses or when combined with other substances, respiratory failure.
- The Huberman Lab Podcast Premium channel supports research on human health and performance, with matching funds from the Tiny Foundation.
Chapter 1

Dr. Huberman introduces the podcast and explains the AMA format.
- Andrew Huberman introduces himself as a professor of neurobiology and ophthalmology at Stanford.
- He explains that the AMA is part of their premium subscriber channel.
- The premium channel supports the free Monday podcasts and funds research.

Chapter 2

Dr. Huberman provides an in-depth explanation of kratom's effects and risks.
- Kratom has stimulant effects at low doses and sedative, analgesic effects at higher doses.
- It is controversial due to its opioid properties and association with the opioid crisis.
- Kratom can be addictive and is hard to come off, leading to withdrawal symptoms.
- There is a debate on whether kratom is a safer alternative to other opioids.

Chapter 3

The premium channel's purpose and benefits are outlined.
- Subscription fees support the standard podcast and fund human health research.
- The Tiny Foundation matches every dollar raised for research.
- Subscribers receive access to extended content and can support scientific endeavors.

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