Jessie's health journey from an accident to exploring glucose's impact on mental health.

• Jessie's health issues began with a back injury and surgery, leading to mental health challenges.
• She pursued health solutions through education in mathematics and biochemistry, and work in genetics.
• Jessie's discovery of glucose's influence on her mental health using a continuous glucose monitor sparked her interest in metabolic health.

Discussing glucose's crucial role in the body and the concept of metabolic flexibility.

• Glucose is the preferred energy source for cells and is consumed through the diet primarily as starches and sugars.
• Metabolic flexibility, the ability to switch between burning glucose and fats, is a critical health aspect that many people lack.
• Lack of metabolic flexibility can lead to constant hunger, energy crashes, and overall poor health.

Exploring differences in eating habits and their effects on metabolic health across cultures.

• French health is declining despite a cultural tendency towards better eating habits, such as longer meal times and less snacking.
• The rise of metabolic issues is becoming more prevalent in France, similar to patterns seen in the U.S., due to modern eating habits.
• Jessie shares an anecdote illustrating the lack of metabolic flexibility in the general population.

Jessie introduces practical techniques to manage glucose spikes and improve health.

• Jessie's books offer hacks to eat carbohydrates with less impact on glucose levels, such as having a savory breakfast and using vinegar.
• These dietary techniques help retrain the mitochondria, regulate hunger hormones, and improve overall well-being.
• Applying these hacks can be beneficial for various health issues, from diabetes to fertility and sleep disorders.

The distinction between glucose and fructose in sugar and their different effects on health.

• The conversation shifts to the difference between eating starches (glucose) and sugars (glucose and fructose).
• Starches are better for health than sugars because they lack fructose, which is harmful in excess.
• Jessie emphasizes the importance of visualizing glucose spikes and the deceptive nature of comparing glucose responses to different foods.

Discussing insulin's function in the body and the issue of insulin resistance.

• Insulin is crucial for health as it helps store excess glucose, but overproduction leads to insulin resistance.
• Insulin resistance is a spectrum leading to type 2 diabetes, and dietary habits play a key role in reversing it.
• Jessie breaks down the hacks from her method to combat insulin resistance, including the timing and composition of meals.

Exploring the cultural differences in food habits between France and the U.S.

• French culture emphasizes fresh food, cooking at home, and taking time to eat, unlike the quick-paced American lifestyle.
• The French paradox is not just about bread and croissants but also about healthy habits like fresh produce and avoiding processed foods.
• The conversation includes insights on the impacts of preservatives, seed oils, and glyphosate on health.